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08.2011 / robo trippin’

DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor[3] and a sigma-1 receptor[4][5] agonist and the action of its major metabolite dextrorphan as an NMDA receptor antagonist, producing effects similar to those of the controlled substances ketamine and phencyclidine (PCP),[6] as well as the active metabolite 3-methoxymorphinan which produces anesthetic effects in rats with a potency above dextrorphan but below dextromethorphan itself.[7] (via)

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